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银屑病临床和基础研究团队

2017/6/3 10:02:28字号:T|T

银屑病临床和基础研究团队是以国医大师禤国维教授为学术顾问,以卢传坚教授为学术带头人,以博士后、博士和青年员工为后续力量的优秀团队,秉承“中西医结合发挥各自所长,优势互补”的原则,长期专注于银屑病相关基础、临床及新药研发等学术研究,同时与澳洲、加拿大、瑞典等国际著名学术机构及国内多家高水平科研院校建立了稳固密切的合作关系,涵盖中医临床、临床研究方法学、中医药标准化、中药药理学、中药制剂学、医学免疫学、分子生物学、系统生物学、网络药理学和计算化学等多学科、多层面联合集体攻关,致力于提高银屑病的综合防治水平并迈向国际化。

Psoriasis clinical and basic research team is an outstanding team, which is guided by the National Chinese Medical Master' academic though of professor Guowei Xuan, led by professor Chuanjian Lu as the core and composed of postdoctoral, doctor and talented young scholars. This team adheres to the principle of " Traditional Chinese and Western medicine play their respective strengths, complementary advantages” and focuses on long-term academic research of psoriasis related basic, clinical, and new drugs. Meanwhile, our team have established close, stable relationship of cooperation with internationally renowned academic institutions in Australia, Canada, Sweden and other countries as well as a number of domestic well-known research institutions to improve the comprehensive prevention and treatment of psoriasis and go forward for the internationalization, which covers TCM Clinic, Clinical Research Methodology, Standardization of TCM, Pharmacology of TCM, Pharmaceutics of TCM, Medical Immunology, Molecular Biology, Systems Biology, Network Pharmacology, Computational Chemistry and so on.

团队主攻方向 Main direction
1.以证结合为核心的临床与基础系统性研究 Combination of disease and syndrome as the core of systematic clinical and basic research

紧密围绕银屑病临床诊疗急需解决的关键问题,以提高临床疗效为导向,结合中西医各自优势开展临床评价与方案优化研究、物质基础与作用机制研究、创新中药研发等系列研究,构建并实施了“源于临床--多学科技术融合--系统研究-回归临床提高疗效的全链条、多方位研究体系,为全面提升银屑病治疗水平奠定基础

Focus on key issues need to be resolved in the clinical diagnosis and treatment of psoriasis and in order to improve the clinical efficacy, our team focus on a series of researches about clinical evaluation, protocol optimization, material basis and mechanism of drug actions, and innovation of TCD combining traditional Chinese and western medicine characteristics and advantages. We have constructed and implemented the clinical basic research system, the whole chain and multi-dimension, of “Origination from clinical-- Multidisciplinary fusion technology-- Systematic research-- Feedback to improve clinical efficacy” to lay the foundation for a comprehensive upgrade the level of psoriasis treatment.



2.银屑病整体证据与综合标准体系的研究 Researches on overall evidence and comprehensive standard system of psoriasis

开展以支撑临床决策为目标的整体证据、综合标准体系研究,以规范临床诊疗,提高综合疗效。目前,团队已系统整理银屑病古今中外文献记载、梳理中医病名源流、病因病机认识、证候分布规律及证候规范,发表10多篇SCI收录文章从多层面对中医或中西医结合治疗银屑病的文献进行系统评价,累计影响因子超过30,是中医或中西医结合治疗银屑病领域发表最多SCI收录文章的团队,目前已经与澳大利亚皇家墨尔本理工大学联合出版《循证临床中医药:寻常型银屑病》英文专著,这是国际首部汇聚中医或中西医结合治疗银屑病整体证据的著作。制定并颁布《寻常型银屑病中西医结合诊疗指南》,这是国内首个银屑病中西医结合诊疗地方标准。

Our team conducts overall-evidence and comprehensive standard system researches for the goal of propping up clinical decision-making, to standardize clinical diagnosis and treatment for the comprehensive efficacy raise. So far, our team has systemic organized ancient and modern literature in Chinese and foreign language, origin of TCM disease names, cognition on etiology and pathogenesis, distribution rules and standards of syndrome, and also reviewed systematically psoriasis literature on treatments of TCM or combination of traditional Chinese and western medicine from multi-layered perspectives. Moreover, we have published more than 10 articles included in SCI, the cumulative impact factor for more than 30, which published the most articles include in SCI in this field. In addition, we have published an English book of “Evidence-based clinical Chinese medicine: psoriasis vulgaris” with Royal Melbourne Institute of Technology in Australia, which firstly collected the overall evidence about treatments of TCM or combination of traditional Chinese and western medicine. Besides, we also have formulated and issued “Diagnostic and treatment guidelines for traditional Chinese and western medicine on psoriasis vulgaris”, which was the first local standard of traditional Chinese and western medicine for diagnoses and treatments in the domestic.
     

3.银屑病生存质量与慢病管理的研究 Researches of survival quality and chronic disease management in psoriasis

顺应社会医学模式转变,在国内率先倡导关注银屑病患者生活质量,积极引进、汉化和评测国际公认的生活质量评测工具,考察和探索其在中国人群的适用性,构建银屑病生存质量评测体系;同时引入国际慢病管理理念,结合中医“治未病”理论,构建国内首个具有中医特色的银屑病慢病管理体系,致力于银屑病的规范管理,预测并防治远期并发症,提高生活质量,减少疾病的危害。

Adapt to the social medical model transformation, we pioneered concerned about psoriasis quality of life in the domestic and actively introduced, Chinesized and evaluated internationally recognized assessment tool about quality of life to study and explore its applicability in Chinese populations for construction of survival quality evaluation system in psoriasis. We also introduced and combined the concept of international chronic disease management with "Preventive treatment of diseases" theory in traditional Chinese medicine to build a management system has the features of traditional Chinese medicine psoriasis chronic disease for standard management of psoriasis, to prevent and control long-term complications, and to improve the quality of life and reduce the harm of disease.


团队主要成员 Members of the team


学术顾问 Academic adviser

       

禤国维  国医大师,广州中医药大学首席教授。先后主持相关课题13个,发表学术论文100多篇,主编、参编教材近20部;先后获国家中医药科技进步奖、广东省中医药科技进步奖、广州中医药大学科技进步奖等多项奖项,被授予“和谐中国十佳健康卫士”、“当代大医精诚代表”等称号,有“岭南皮肤圣手”之称。

Professor Guowei Xuan, National Medical Master, chair Professor of Guangzhou University of Chinese Medicine. He took charge of 13 research topics at all, and published more than 100 academic articles and over 20 publications. He also has won the National Medical Science and Technology Progress Award, Guangdong Province Traditional Chinese Medicine Science and Technology Progress Award, the Guangzhou University of Chinese Medicine Science and Technology Progress Award and so on. Moreover, he was honored as  “China Top Ten harmony health guards”, “Representatives of contemporary medicine sincere” ,“Hand of Dermatology in Lingnan ”,ect.

学术带头人 Academic leader

      

卢传坚  广州中医药大学教授、主任医师、博士生导师、广东省“千百十”工程国家级人才培养对象兼任澳大利亚墨尔本皇家理工大学名誉教授和博士生导师、中华中医药学会免疫分会主任委员、世界中医药学会联合会免疫学分会副会长、广东省中医药标准化技术委员会主任委员。曾主持并完成国家中医药行业重大专项、国家"十一五"科技支撑计划及国家自然科学基金项目等国家及省部级课题项目多项。目前主持国家"十二五"科技支撑计划、国家自然科学基金、省市科技计划及省自然科学基金团队项目等多个项目。主编出版专著16部,其中中文专著11部,英文专著5部;以第一作者及通讯作者发表所发表相关学术论文120篇余,其中SCI收录40篇;获得国家发明专利授权和软件著作权共4项,获广东省科技进步奖、广东省教育教学成果奖、中华中医药学会科学技术奖等省部级教学、科研成果奖共11项。曾荣获"全国优秀科技工作者"、"全国首届杰出女中医师"、"第二届全国百名杰出青年中医""中华中医药学会科技之星"、“中国女医师协会五洲女子科技奖”等称号。

Professor Chuanjian Lu , Chief physician, professor of Guangzhou University of Chinese Medicine, the object of national cultivation for talent in Guangdong Provincial “qianbaishi project”, Honorary professor and doctoral supervisor of the Australia's RMIT University.Director of Immunology Branch in China Association of Chinese Medicine. Vice-chairman of Immunology Association in World Federation of Chinese Medicine Societies. Director of Guangdong Provincial Standardization Technical Committee of TCM. She chaired and completed several projects include State significant projects of TCM industry, National "Eleventh Five-Year" Technology Support Program, Natural Science Foundation of China (NSFC) and other provincial projects. Currently, she is in charge of National “Twelfth Five-Year" Technology Support Program, Natural Science Foundation of China (NSFC) and team project of Guangdong Provincial Natural Science Foundation. She has edited 16 publications (Chinese for 11 and English for 5), published about 120 papers (SCI for 40) in professional academic journal. Furthermore, she has obtained 4 national invention patents/software copyrights, and accepted 11 awards of teaching and research such as Guangdong Provincial teaching achievement award, Association of Chinese Medicine Science and Technology Second Award. In addition, she was award as “National excellent workers in science and technology ”, “National outstanding female physicians for TCM”, “National hundred-outstanding young traditional Chinese physicians”, “Science and technology stars of China association of TCM”, “Wuzhou Women Technology Award of China Medical Women's Association ” and so on.

学术骨干Academic backbone

      

闫玉红  医学博士、博士后,副主任医师,广东省中医药学会皮肤科分会委员,中华中医药学会免疫学分会理事。主持省部级课题2项,参与银屑病相关省部级课题5项,作为副主编参编皮肤病专著3部,发表核心期刊相关论文多篇,参与专利1项,获得中华中医药学会科学技术奖2项

Yuhong Yan, Doctor of Medicine, Postdoctor, Associate chief physician, Member of Dermatology Branch of Guangdong Provincial Association of TCM. Member of Immunology Branch in China Association of Chinese Medicine. She has chaired 2 the provincial projects, participated in 5 province projects psoriasis associated and deputy edited of dermatology publishes. She has also published a number of academic articles, participated in a patent obtained and got 2 Chinese Medicine Institute of Science and Technology Award.

    

姚丹霓 医学博士、主治医师。目前主持广东省中医药管理局课题《皮肤病生活质量指数(DLQI)在中医药治疗寻常型银屑病中的临床最小重要差值研究》1项,参与银屑病相关国家级及省部级课题共4项。发表相关论文5篇,参编出版皮肤病专著2部。

Danni Yao, Doctor of Medicine, Attending physician. She is chairing the Guangdong province administration of traditional Chinese medicine (Dermatology Life Quality Index (DLQI) in Chinese medicine psoriasis clinical study treatment minimal important difference), and participated in relevant national and provincial psoriasis projects a total of four. She has also published 5 papers and edited two monographs published in dermatology.

    

邓静文  医学硕士,助理研究员。曾赴美国亨利福特医院皮肤免疫学研究室进修,聚焦朗格汉斯细胞、NKTcellMicroRNA主攻银屑病发病机制及中医药治疗银屑病的免疫学机制。参与银屑病相关国家级及省部级课题共4项,发表SCI 论文6篇。

Jingwen Deng, Master of Medicine, Assistant researcher. She has been researched on Langerhans cells, NKTcell, MicroRNA in skin immunology laboratory of the Henry Ford hospital in the United States. Her current research interests includes the pathogenesis of psoriasis and Chinese medicine treatment of psoriasis immunological mechanisms. She has also participated in relevant national and provincial psoriasis projects a total of four and published 6 articles included in SCI.

       

陈海明  中药学博士、在站博士后,主攻中医药防治银屑病的药效及机制研究。2014年赴香港中文大学中医学院进修,从事抗中药活性筛选及分子机理研究。以第一作者及并列第一作者发表并收录于SCI论文共7篇,中文核心期刊6篇。

Haiming Chen, Doctor of Chinese materia medica, Postdoctor, current research interests in the efficacy of TCM prevention and treatment of psoriasis and its mechanism of action. He has been to college of traditional Chinese medicine of the Chinese University of Hong Kong School in 2014. He has published 7 articles, served as first author and co-first author, included in SCI and 6 articles in Chinese professional academic journal.

   

邓浩  医学硕士,以银屑病的临床与基础研究为主攻方向,参与银屑病相关国家级及省部级课题共4项,参编出版皮肤病专著2部。

Hao Deng, Master of Medicine, major directions for psoriasis disease. He has also participated in relevant national and provincial psoriasis projects a total of four and published 2 skin disease monographs.


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