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中医药防治绝经相关疾病研究团队

2017/7/6 8:52:42字号:T|T

绝经相关疾病研究团队于2010年成立,其前身为1988年成立的广东省中医院绝经相关疾病专科。多年来,本团队在中医理论指导下,结合现代医学的研究进展,围绕绝经综合征、原发性卵巢功能不全、绝经后心血管疾病等绝经相关领域开展了一系列临床及基础研究。

Research group of Treating menopause related disease with Chinese Medicine was founded in 2010grew out of menopause sub-specialty of gynecology department in Guangdong provincial hospital of Chinese medicine(CM) founded in 1988. Under the guidance of the basic theory of TCM , we have done series of clinical and basic researches mainly on the menopause syndrome, primary ovarian insufficiency and post menopause related disease.

团队主攻方向  Main direction

1.中医药治疗绝经综合征的研究 TCM on Menopause syndrome

针对绝经综合征多系统的临床特点我们形成中医病证结合诊疗规范。目前是国家中医药管理局“十一五”重点专科(专病)协作组绝经疾病牵头单位。相关诊疗措施如中医情志疗法操作规范在全国推广应用;针对常见的中医证型,自主研发更年滋肾口服液、养阴疏肝胶囊等药物。

We have developed treatment strategies of menopause syndrome based on the combination of disease and TCM syndrome differentiation” theory. We are the leader group of menopause related disease in the "Eleventh fifth" key specialized subject of National TCM Administration. For treating different menopause related symptom, we have developed series TCM patent medicine and TCM psychological therapy practices.


2.绝经综合征中医药疗效评价研究 Clinical effective evaluation research of Chinese medicine on menopause syndrome

基于中医理论体系和中国人群特点我们研制了适合中医药疗效评价的绝经综合征评定量表确立中医药治疗绝经综合征疗效评价体系目前已在全国推广应用。

Under the guidance of the basic theory of TCM, We have developed the Chinese menopause scale according to characteristic of Chinese womenwhich has been promoted in Chine in recent years.  

3.中医药防治绝经后相关疾病临床研究  TCM on post menopause related disease

绝经后心血管疾病是绝经后女性的头号杀手。本团队针对心血管疾病的高危因素血脂异常和代谢综合征,在围绝经期(绝经早期)采用中药干预,以期延缓或减少绝经后疾病的发生。

Cardiovascular disease(CVD) is the leading killer for the post menopause women. Our research focuse on dyslipidemia and metabolic syndrome in peri-menopause womenwhich would delay or reduce the post menopause CVD in early stage by giving effective intervention.

4.中医药防治卵巢功能低下的研究 TCM on primary ovarian insufficiency (POI)

原发性卵巢功能低下严重影响了女性的生殖健康。我们开展了一系列中医药针对卵巢功能低下的临床和基础研究,目前研究已经显示,中药促进POI患者卵泡复苏并可能延缓POI进程。

Primary ovarian insufficiencyPOIaffect the women's reproductive health seriously. We have carried out a series clinical and basic researches of Chinese medicine on POIwhich showed Chinese Medicine could elevated the follicular recovery and might delay the process of POI.

5.绝经相关疾病中医药健康管理平台建设 TCM Health management platform of menopause related disease 

绝经相关疾病需要药物饮食、运动、心理支持等综合健康管理。我们充分发挥中医药“治未病”的优势,搭建了中医健康管理平台,进行长时间管理,减少绝经症状和绝经后疾病发生,提高女性健康水平。

Integrated health managements include medicine, diet, exercise and psychological support .Playing the advantage of Chinese medicine prevention conceptionwe develop the healthy management platform of Chinese medicine on menopause related disease and make a long term management plan for improving the menopause womens quality of life.

团队主要成员 Main members of the group

学术带头人 Academic consultant

    

王小云:主任医师,广东省中医院大妇科主任,主持国家科技部国家科技支撑计划、部省级课题等多项,获国家教育部及广东省科技厅奖项。

Professor Wang Xiaoyun, chief physician, director of gynecology department of Guangdong hospital of TCM,, mainly responsible for several national projects and gained several technological achievement prize.

团队负责人 Group leader:

   

杨洪艳:主任医师,广东省中医院绝经团队负责人。主持国家自然科学基金、国家支撑计划以及省部级课题多项。

Professor Yang Hongyan, chief physician ,leader of research group of Chinese  medicine on menopause related disease,mainly responsiblefor several national natural science fund projects and provincial projects.

团队骨干 Team backbone

   

聂广宁:副主任医师发表SCI及核心期刊学术论文10余篇,主持和主要参与国家和省级科研课题10余项。

Dr Nie Guangning , vice physician. mainly responsiblefor several provincial projects.


附:主要课题

课题名称

负责人

任务来源

级别

经费

(万元)

二仙汤有效组分配伍通过MAPKsNrf2/ARE通路对人卵巢颗粒细胞氧化应激保护作用

The antioxidative effect of ingredients assembling of Er-xian decoction on ovarian granulose cells by MAPKs and Nrf2/ARE.

杨洪艳

国家自然科学基金

国家

23

妇女更年期综合征中医证治规律研究

The research on the rule of TCM Syndrome on Menopause syndrome

王小云

国家科技十五攻关项目

国家

70

绝经综合征中医药疗效评价研究

The Development and Evaluation of Chinese Menopause Rating Scale

王小云

国家科技十五攻关项目

国家

230

中医异病同治治疗绝经综合征、经前期综合征临床研究。

The clinical research on menopause syndrome and premenstrual syndrome using Chinese medicine principle of homotherapy for heteropathy

王小云

国家科技部十一五支撑计划

国家

70

中医病症结合治疗绝经综合征临床研究

Effect of Combining Therapy with disease and Chinese syndrome in Women with Menopausal Syndrome: A Randomized Controlled Clinical Trial

王小云

国家中医临床研究基地

国家

210

中药促特发性原发性卵巢功能不全患者卵泡复苏作用的临床研究

Clinical study of promoting follicle recovery in  patients with idiopathic with treating by primary ovarian insufficiency Traditional Chinese medicine

杨洪艳

广东省科技厅

省部

30

绝经相关疾病中医药健康管理

Health management of Chinese medicine on menopause related disease

王小云

广东省财厅

省部

150

绝经综合征中医药研究

Chinese medicine on Menopause syndrome

王小云

广东省政府中医药强省专项

厅局

300

更年滋肾口服液治疗绝经综合征新药临床前开发研究

New drugs development research of “Gengnianzishen liquid” on menopause  syndrome

王小云

广东省财厅

省部

100

主要论文

1. Hongyan YangJing YangZehuai WenQinglin ZhaGuangning NieXuchun HuangChunlinZhangAiping LuMiao Jiang*Xiaoyun Wang* Effect of combining therapy with traditional Chinese medicine-based psychotherapy and herbal medicines in women with menopausal syndrome: a randomized controlled clinical trial. The journal of alternative and complementary medicine2012

2. Wang XY*, Nie GN, Yang HY, Zong LL. Chinese Medicine for Menopausal Syndrome: Current Status,Problems and Strategies. Chinese Journal of Integrative Medicine, 2011,12: 889-892.

3. Hongyan Yang, Xiaoyun Wang*, Xuying, et al. A randomized controlled trial of the "Psychotherapy and Physical therapy" of Traditional Chinese Medicine on Menopause Syndrome with depress. Journal of Guangdong Medicine, 2011, 16: 2209-2211.

4. Hongyan Yang*, Min KuangXiaoyun Wang. Retrospective study of Traditional Chinese medicine in treating ovarian aging. Journal of Guangdong Medicine, 2011, 14:1924-1926.

5. Guangning Nie,Xiaoyun Wang*, Hongyan Yang. Study on relationship of menopause symptoms with menopause status in 3343 menopause women. Journal of liaoning traditional Chinese medicine, 2011, 07:1270-1273.

6. Hongyan Yang*, Qiuhua Wang, Xiaoyun Wang. The literature study on traditional Chinese medicine syndrome of menopause syndrome using Content analysis. Journal of New Chinese Medicine, 2011, 07:122-125.

7. Guangning Nie,Xiaoyun Wang*, Hongyan Yang. Test and adjustment research of Chinese Menopause Syndrome Rating Scale. Journal of traditional Chinese medicine, 2011, 04:461-462.

8. Guangning Nie,Xiaoyun Wang*, Hongyan Yang. Investigation on factors of Chinese urban female menopause age. Chinese journal of maternal and child health, 2011, 08:1191-1193.

9. Xiaoyun Wang*, Guangning Nie, Hongyan Yang, et al. Confirmatory factor analysis of Chinese Menopause Syndrome Rating Scale. Journal of PLA postgraduated medical school,2010,05:440-441.

10. Xiaoyun Wang*, Hongyan Yang, Guangning Nie, et al. Study of theoretical construct of Chinese Menopause Syndrome Rating Scale. Journal of Liaoning traditional Chinese medicine, 2010,04:610-612.

11.Xu Ying, LiuJIan, WANG Xiao yun.Prof.wang xiao yun,s Experience in Treating Climacteric Syndrome from the Pathogenesis of Kidney Deficiency and Liver Stagnancy. Joumal of Traditional Chinese Medicine, March  2010,Vol.30.No.1

 

 


 










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